Adel NEYAZ
PhD Student
MTech. Bioscience & Bioengineering | Indian Institute of Technology, Jodhpur, India
BE | Panjab University, Chandigarh, India
About
Adel Neyaz is a PhD candidate at Nanyang Technological University (NTU), Singapore, where he conducts research at the interface of molecular biology and computational genomics. He has developed strong expertise in bioinformatics and transcriptomic analysis, working extensively with both bulk and single-cell RNA sequencing data.
His research integrates experimental and computational approaches, combining hormone treatment models with genomic data analysis to investigate complex regulatory systems. Through his training, Adel has cultivated a strong interest in gene regulation, endocrine signaling, and genomic data analysis.
Project
Adel’s research focuses on understanding the role of progesterone receptor (PGR) signaling, particularly the activation function 1 (AF1) domain, in regulating uterine biology. Using ovariectomized mouse models and hormone treatments involving estrogen and progesterone, his work investigates how PGR-AF1 drives gene- and cell type-specific transcriptional responses in the endometrium.
His study integrates multiple genomic approaches, including RNA-seq, single-cell transcriptomics, and ChIP-seq, to uncover how estrogen and progesterone signaling pathways coordinate within the endometrium. By establishing a mechanistic framework for PGR-AF1 function, Adel’s research provides new insights into early pregnancy biology and uterine health, with broader implications for reproductive disorders and hormone-driven diseases.