Publications
CLICK HERE for all publications. *co-first authors; bold, Thibault lab members; ✉corresponding author.
orcid.org/0000-0002-7926-48122023
2022
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R. Dudkevich, Jhee Hong Koh, Caroline Beaudoin-Chabot, Cenk Celik, I. Lebenthal-Loinger, S. Karato-Lampert, Syed Ahmad-Albukhari, Guillaume Thibault, S. Henis-Korenblit✉
Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism Cell Reports 2022 Nov 29. doi.10.1016/j.celrep.2022.111739 Abstract | Full Text | PDF |
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Wei Sheng Yap and Guillaume Thibault✉
A new combinatorial megaplasmid library assembly method designed to screen for minimal pathways by using SCRaMbLE MicroPubl Biol 2022 Oct 26. doi.10.17912/micropub.biology.000657 Abstract | Full Text | PDF | Data Repository |
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Caroline Beaudoin-Chabot*, Lei Wang*, Cenk Celik, Aishah T.F. Abdul Khalid, Subbash Thalappilly, Shiyi Xu, Jhee Hong Koh, Venus W.X. Lim, Ann Don Low, and Guillaume Thibault✉
The unfolded protein response reverses the effects of glucose on lifespan in chemically-sterilized C. elegans Nat Commun 2022 Oct 19. doi. 10.1038/s41467-022-33630-0 Abstract | Full Text | PDF | Data Repository NTU NEWS | NTU Press Release Local Media Coverage CNA938 Singapore Today, Straits Times, zaobao International Media Coverage Big News Network, Borneo Bulletin, Canaltech, Forbes Russia, Psychreg, Revyuh, terra, and Yahoo! News |
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Wei Sheng Yap and Guillaume Thibault✉
Human PERK rescues unfolded protein response-deficient yeast cells MicroPubl Biol 2022 Jun 22. doi. 10.17912/micropub.biology.000592 Abstract | Full Text | PDF | Data Repository |
2021
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K. Rizzolo, A.Y.H. Yu, A. Ologbenla, S.R. Kim, H. Zhu, K. Ishimori, Guillaume Thibault, E. Leung, Y.W. Zhang, M. Teng, M. Haniszewski, N. Miah, S. Phanse, Z. Minic, S. Lee, J.D. Caballero, M. Babu, F.T.F. Tsai, T. Saio, W.A. Houry
Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex Nat Commun 2021 Jan 12. doi. 10.1038/s41467-020-20553-x Abstract I Full Text I PDF |
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Guillaume Thibault, Davis T. Ng, Vikash Verma
Concepts | Heat/Stress Responses Encyclopedia of Biological Chemistry III, Academic Press, Waltham, 2021, 97-101. doi. 10.1016/B978-0-12-819460-7.00189-4 Full Text |
2020
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Wei Sheng Yap*, Peter Shyu Jr.*, Maria Laura Gaspar, Stephen A. Jesch, Charlie Marvalim, William A. Prinz, Susan A. Henry, Guillaume Thibault✉
The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis J Cell Sci 2020 Nov 5. doi. 10.1242/jcs.248526 Abstract I Full Text I PDF I Data Repository Article was featured in Research Highlight Wei Sheng Yap was featured as First Person in the same issue Preprint of this pubilcation was highlighted in preLights |
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Nurulain Ho*, Wei Sheng Yap*, Jiaming Xu*, Haoxi Wu*, Jhee Hong Koh, Wilson W.B. Goh, Bhawana George, Shu Chen Chong, Stefan Taubert, Guillaume Thibault✉
Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress J Cell Biol 2020 Apr 29. doi. 10.1083/jcb.201909165 Abstract I Full Text I PDF I Data Repository |
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Rachel S. Kraut, Guillaume Thibault, Sarita Hebbar, Elisabeth Knust, eds.
Connections to Membrane Trafficking Where You Least Expect Them: Diseases, Dynamics, Diet and Distance Frontiers Media SA. doi. 10.3389/978-2-88963-429-3 Ebook PDF I Ebook EPUB |
2019
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Kizito Njah, Sayan Chakraborty, Beiying Qiu, Surender Arumugam, Anandhkumar Raju, Ajaybabu V. Pobbati, Manikandan Lakshmanan, Vinay Tergaonkar, Guillaume Thibault, Xiaomeng Wang, Wanjin Hong
A Role of Agrin in Maintaining the Stability of Vascular Endothelial Growth Factor Receptor-2 during Tumor Angiogenesis Cell Rep 2019 Jul 23. doi. 10.1016/j.celrep.2019.06.036 Abstract I Full Text I PDF |
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Peter Shyu Jr*, Benjamin S.H. Ng*, Nurulain Ho, Ruijie Chaw, Yi Ling Seah, Charlie Marvalim, Guillaume Thibault✉
Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins Sci Rep 2019 Jun 14. doi. 10.1038/s41598-019-45020-6 Abstract I Full Text I PDF |
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Caroline Beaudoin-Chabot, Lei Wang, Alexey V. Smarun, Dragoslav Vidovic, Mikhail S. Shchepinov, Guillaume Thibault✉
Deuterated polyunsaturated fatty acids reduce oxidative stress and extend the lifespan of C. elegans Front Physiol 2019 May 28. doi. 10.3389/fphys.2019.00641 Abstract I Full Text I PDF I Data Repository |
2018
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Jhee Hong Koh*, Lei Wang*, Caroline Beaudoin-Chabot, Guillaume Thibault✉
Lipid bilayer stress-activated IRE-1 modulates autophagy during endoplasmic reticulum stress J Cell Sci 2018 Nov 21. doi. 10.1242/jcs.217992 Abstract I Full Text I PDF I Data Repository |
2014
2013
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Chengchao Xu, Songyu Wang, Guillaume Thibault, Davis T. Ng
Futile Protein Folding Cycles in the ER Are Terminated by the Unfolded Protein O-Mannosylation Pathway Science 340, 978-981. doi. 10.1126/science.1234055 Abstract I Full Text I Perspective in Science I Research Highlights in Nature Chemical Biology I Faculty Opinions |
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Guillaume Thibault✉ and Davis T. Ng
Heat/Stress Responses Encyclopedia of Biological Chemistry, Academic Press, Waltham, 2013, 522-525. doi. 10.1016/B978-0-12-378630-2.00427-8 Full Text |
2012
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Guillaume Thibault , Guanghou Shui, Woong Kim, Graeme C. McAlister, Nurzian Ismail, Steven P. Gygi, Markus R. Wenk, Davis T. Ng
The membrane stress response buffers lethal effects of lipid disequilibrium by reprogramming the protein homeostasis network Mol Cell 48, 16-27. doi. 10.1016/j.molcel.2012.08.016 Abstract I Full Text I PDF I Featured on the Cover I Faculty Opinions |
2011
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Usheer Kanjee, Irina Gutsche, Eftichia Alexopoulos, Boyu Zhao, Majida El Bakkouri, Guillaume Thibault, Kaiyin Liu, Shaliny Ramachandran, Jamie Snider, Emil F. Pai. Walid A. Houry
Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase EMBO J 30, 931-944. doi. 10.1038/emboj.2011.5 Abstract I Full Text I PDF I Faculty Opinions |
2008
2006
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Guillaume Thibault, Jovana Yudin, Philip Wong, Vladimir Tsitrin, Remco Sprangers, Rongmin Zhao, Walid A. Houry
Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX Proc Natl Acad Sci U S A 103, 17724-17729. doi. 10.1073/pnas.0601505103 Abstract I Full Text I PDF |
2003
Preprint replaced by peer-reviewed publications
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Peter Shyu Jr, Wei Sheng Yap, Maria Laura Gaspar, Stephan A. Jesch, Charlie Marvalim, William A. Prinz, Susan A. Henry, Guillaume Thibault✉
Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis bioRxiv 2020 April 15. doi. 10.1101/2020.04.06.027847 Abstract I PDF This preprint is highlighted in preLights doi. 10.1242/prelights.19358 |
