Biography • Principal Investigator
Guillaume Thibault PhD is a biochemist/cell biologist with 20 years of experience in cellular stress responses and quality control. He obtained his Ph.D. under the supervision of Prof Walid Houry from the Department of Biochemistry, University of Toronto, Canada. He was then a postdoc in Dr Davis Ng’s laboratory at Temasek Life Sciences Laboratory, Singapore. He joined the School of Biological Sciences (SBS) at Nanyang Technological University (NTU) to set up his research programme focusing on cellular stress and lipid homeostasis with funding from the prestigious Elite Nanyang Assistant Professorship Award and was subsequently promoted to Associate Professor (tenured). He secured more than S$ 3.3M in external funding as a principal investigator at SBS, NTU. He has published 33 papers and has an h-index of 19. He holds a joint appointment as co-Principal Investigator at the Mechanobiology Institute, National University of Singapore and as Adjunct Principal Investigator, Institute of Molecular and Cell Biology, A*STAR. He is also the founding President of the Society for Cell Biology Singapore (SCBS).
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Guillaume THIBAULT, PhD
Associate Professor
School of Biological Sciences
Nanyang Technological University
60 Nanyang Drive, SBS-03n-27
Singapore 637551
Tel +65 6592 1787
thibault@ntu.edu.sg
Twitter @Guillou76
Associate Professor
School of Biological Sciences
Nanyang Technological University
60 Nanyang Drive, SBS-03n-27
Singapore 637551
Tel +65 6592 1787
thibault@ntu.edu.sg
Twitter @Guillou76
Employment History
2022-curr • Associate Professor (tenured), School of Biological Sciences, Nanyang Technological University
2021-curr • Co-Principal Investigator, Mechanobiology Institute, National University of Singapore (MBI), Singapore
2019-curr • Adjunct Principal Investigator, Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore
2013-2022 • Assistant Professor, School of Biological Sciences, Nanyang Technological University
2008-2013 • Postdoctoral Research Fellow, Temasek Life Sciences Laboratory, National University of Singapore
2004-2006 • Treasurer (elected position), Graduate Students’ Union (GSU), University of Toronto, Canada
1996-2000 • Research Technician, INRS – Institut Armand-Frappier, Université of Québec, Canada
2021-curr • Co-Principal Investigator, Mechanobiology Institute, National University of Singapore (MBI), Singapore
2019-curr • Adjunct Principal Investigator, Institute of Molecular and Cell Biology (IMCB), A*STAR, Singapore
2013-2022 • Assistant Professor, School of Biological Sciences, Nanyang Technological University
2008-2013 • Postdoctoral Research Fellow, Temasek Life Sciences Laboratory, National University of Singapore
2004-2006 • Treasurer (elected position), Graduate Students’ Union (GSU), University of Toronto, Canada
1996-2000 • Research Technician, INRS – Institut Armand-Frappier, Université of Québec, Canada
Academic Qualifications
2013 • Postdoctoral Research Fellow, Temasek Life Sciences Laboratory, National University of Singapore
2007 • Ph.D. in Biochemistry, University of Toronto, Canada
2002 • B.Sc. in Biochemistry, Université du Québec à Montréal, Canada
1999 • Diploma in Analytical Chemistry, Collège Ahuntsic, Canada
2007 • Ph.D. in Biochemistry, University of Toronto, Canada
2002 • B.Sc. in Biochemistry, Université du Québec à Montréal, Canada
1999 • Diploma in Analytical Chemistry, Collège Ahuntsic, Canada
Publications
Google Scholar Profiles
Loop Profile
ORCID 0000-0002-7926-4812 Profile
Publons Profile
PubMed - all publications
Scopus Profile
Loop Profile
ORCID 0000-0002-7926-4812 Profile
Publons Profile
PubMed - all publications
Scopus Profile
Funding and Awards
2023-2025 • MOE AcRF Tier 1 September 2022 Grant Call, Exploring the role of the endoplasmic reticulum in epithelial cell differentiation, Lead PI.
2023-2025 • MOE AcRF Tier 1 March 2022 Grant Call, Connect choline deficiency during pregnancy with unfolded protein response and Alzheimer diseases, Co-PI.
2021-2026 • MOE AcRF Tier 3 2020, Endomembrane System Dynamics, Architecture, and Functions in Aging Cells and Tissues, Team PI.
2021-2025 • NMRC OF-IRG November 2019 Grant Call, Targeting Host-Pathogen Synergy in Wound Infection, Lead PI.
2020-2022 • MOE AcRF Tier 1 September 2019 Grant Call, Adaptor protein WDFY3 is neuroprotective by counteracting age-mediated decline in proteostasis, Lead PI.
2019-2022 • 3rd NRF-NSFC Grant Call, Identify essential genes to construct a functional unfolded protein response programme using synthetic biology, Lead PI.
2019-2021 • NTU EdeX Grant, Improving student learning using open-ended question assessment with machine learning-driven immediate feedback, Lead PI.
2018-2021 • MOE AcRF Tier 2 February 2018 Grant Call, Characterising the anti-aging role of the UPR from high glucose diet, Lead PI.
2016-2018 • MOE, AcRF Tier 1 Grant, Elucidating Exosomes Biogenesis and Uptake in Cancer Progression, Lead PI.
2016-2018 • MOE AcRF Tier 1 Grant, Catalytic Synthesis and Metabolism of Site-Specific Deuterated Essential Fatty Acids, Lead PI.
2015-2016 • MOE AcRF Tier 1 Grant, From Dietary Excess to Neurodegeneration: Finding the Missing Links in Vesicular Autophagy Transport, Degradation, and Stress, Lead PI.
2013-2016 • The Elite Nanyang Assistant Professorship Award 2013, Nanyang Technological University.
2009-2011 • Singapore Millennium Foundation Post-Doctoral Award (competitive fellowship).
2006-2007 • Fonds de Recherche sur la Nature et les Technologies du Québec Graduate Scholarship.
2006 • David A. Scott Award, Department of Biochemistry – University of Toronto (DB-UofT). Best all-round Graduate Student.
2004-2006 • Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship (PGS D), Doctoral research.
2004 • Bradley Pett Graduate Award for academic excellence, DB-UofT.
2004 • Beckman Coulter Award for best first-author publication, DB-UofT.
2003 • 3rd place poster award (M.Sc. category), DB-UofT.
2002-2004 • NSERC Postgraduate Scholarship (PGS A), Master research.
2002 • NSERC Undergraduate Student Research Award, UofT.
2002 • Boehringer Ingelheim Award in biochemistry for academic excellence, UQAM Foundation.
2023-2025 • MOE AcRF Tier 1 March 2022 Grant Call, Connect choline deficiency during pregnancy with unfolded protein response and Alzheimer diseases, Co-PI.
2021-2026 • MOE AcRF Tier 3 2020, Endomembrane System Dynamics, Architecture, and Functions in Aging Cells and Tissues, Team PI.
2021-2025 • NMRC OF-IRG November 2019 Grant Call, Targeting Host-Pathogen Synergy in Wound Infection, Lead PI.
2020-2022 • MOE AcRF Tier 1 September 2019 Grant Call, Adaptor protein WDFY3 is neuroprotective by counteracting age-mediated decline in proteostasis, Lead PI.
2019-2022 • 3rd NRF-NSFC Grant Call, Identify essential genes to construct a functional unfolded protein response programme using synthetic biology, Lead PI.
2019-2021 • NTU EdeX Grant, Improving student learning using open-ended question assessment with machine learning-driven immediate feedback, Lead PI.
2018-2021 • MOE AcRF Tier 2 February 2018 Grant Call, Characterising the anti-aging role of the UPR from high glucose diet, Lead PI.
2016-2018 • MOE, AcRF Tier 1 Grant, Elucidating Exosomes Biogenesis and Uptake in Cancer Progression, Lead PI.
2016-2018 • MOE AcRF Tier 1 Grant, Catalytic Synthesis and Metabolism of Site-Specific Deuterated Essential Fatty Acids, Lead PI.
2015-2016 • MOE AcRF Tier 1 Grant, From Dietary Excess to Neurodegeneration: Finding the Missing Links in Vesicular Autophagy Transport, Degradation, and Stress, Lead PI.
2013-2016 • The Elite Nanyang Assistant Professorship Award 2013, Nanyang Technological University.
2009-2011 • Singapore Millennium Foundation Post-Doctoral Award (competitive fellowship).
2006-2007 • Fonds de Recherche sur la Nature et les Technologies du Québec Graduate Scholarship.
2006 • David A. Scott Award, Department of Biochemistry – University of Toronto (DB-UofT). Best all-round Graduate Student.
2004-2006 • Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship (PGS D), Doctoral research.
2004 • Bradley Pett Graduate Award for academic excellence, DB-UofT.
2004 • Beckman Coulter Award for best first-author publication, DB-UofT.
2003 • 3rd place poster award (M.Sc. category), DB-UofT.
2002-2004 • NSERC Postgraduate Scholarship (PGS A), Master research.
2002 • NSERC Undergraduate Student Research Award, UofT.
2002 • Boehringer Ingelheim Award in biochemistry for academic excellence, UQAM Foundation.
Teaching
BS3022 Protein Trafficking • Course Coordinator
BS3340 Science of aging and life extension in C. elegans • Course Coordinator
BS3340 Science of aging and life extension in C. elegans • Course Coordinator
Service and Committees
2023-curr • Associate Editor, Molecular Biology of the Cell (MBoC).
2023-curr • Vice-President, Society for Cell Biology Singapore (SCBS).
2022-curr • Assistant Chair (Graduate Education), School of Biological Sciences, NTU.
2022-curr • Associate Member, American Society for Cell Biology (ASCB) International Affairs Committee.
2022-2023 • Founding President, Society for Cell Biology Singapore (SCBS).
2022 • Minisymposia Co-Chair, ASCB│EMBO Cell Bio 2022, Cells in Distress and Disease – Endomembrane trafficking in health and diseases, Washington DC, USA.
2021-curr • Co-Organizer, FASEB meeting 2023 and 2025, The Endoplasmic Reticulum (ER) Conference: Structure, Function, and Disease, Melbourne, FL, USA.
2020-curr • Chair, SBS Outreach Committee.
2019-curr • Coordinator, Graduate Student Seminar Series, School of Biological Sciences, NTU.
2017-curr • International Scientific Program Committee Member, Asia-Pacific Worm Meeting, Seoul, South Korea (2018); Taipei, Taiwan (2020 cancelled due to COVID-19; postponed to 2022).
2021 • International Meeting Session Organizer and Chair, ASCB│EMBO 2021 Meeting, subgroup session The Interplay Between Lipids and Proteins in the Endoplasmic Reticulum (ER): How the ER is the Master Regulator of the Cell Universe, Virtual (2021).
2019 • International Meeting Session Organizer and Chair, ASCB│EMBO 2019 Meeting, subgroup session Lipids and Proteins in the Secretory Pathway - Homeostasis and Stress, Washington, DC, USA.
2018-2019 • Editor for the Research Topic "Connections to Membrane Trafficking Where you Least Expect Them: Diseases, Dynamics, Diet and Distance" in Frontiers in Cell and Developmental Biology and Frontiers in Physiology
2017 • International Meeting Session Organizer and Chair, ASCB│EMBO 2017 Meeting, subgroup session The Intersection of Lipids and Proteins in the Secretory Pathway, Philadelphia, PA, USA.
2015 • International Meeting Session Organizer and Chair, ASCB Annual Meeting 2015, subgroup session Dynamic Interplay between Lipids, Curvatures, and Diseases of Biological Membranes, San Diego, CA, USA.
2010-2013 • F1000 Associate Faculty Member. Regularly contributing evaluation of papers published in biological sciences to the Faculty of 1000 Biology.
2023-curr • Vice-President, Society for Cell Biology Singapore (SCBS).
2022-curr • Assistant Chair (Graduate Education), School of Biological Sciences, NTU.
2022-curr • Associate Member, American Society for Cell Biology (ASCB) International Affairs Committee.
2022-2023 • Founding President, Society for Cell Biology Singapore (SCBS).
2022 • Minisymposia Co-Chair, ASCB│EMBO Cell Bio 2022, Cells in Distress and Disease – Endomembrane trafficking in health and diseases, Washington DC, USA.
2021-curr • Co-Organizer, FASEB meeting 2023 and 2025, The Endoplasmic Reticulum (ER) Conference: Structure, Function, and Disease, Melbourne, FL, USA.
2020-curr • Chair, SBS Outreach Committee.
2019-curr • Coordinator, Graduate Student Seminar Series, School of Biological Sciences, NTU.
2017-curr • International Scientific Program Committee Member, Asia-Pacific Worm Meeting, Seoul, South Korea (2018); Taipei, Taiwan (2020 cancelled due to COVID-19; postponed to 2022).
2021 • International Meeting Session Organizer and Chair, ASCB│EMBO 2021 Meeting, subgroup session The Interplay Between Lipids and Proteins in the Endoplasmic Reticulum (ER): How the ER is the Master Regulator of the Cell Universe, Virtual (2021).
2019 • International Meeting Session Organizer and Chair, ASCB│EMBO 2019 Meeting, subgroup session Lipids and Proteins in the Secretory Pathway - Homeostasis and Stress, Washington, DC, USA.
2018-2019 • Editor for the Research Topic "Connections to Membrane Trafficking Where you Least Expect Them: Diseases, Dynamics, Diet and Distance" in Frontiers in Cell and Developmental Biology and Frontiers in Physiology
2017 • International Meeting Session Organizer and Chair, ASCB│EMBO 2017 Meeting, subgroup session The Intersection of Lipids and Proteins in the Secretory Pathway, Philadelphia, PA, USA.
2015 • International Meeting Session Organizer and Chair, ASCB Annual Meeting 2015, subgroup session Dynamic Interplay between Lipids, Curvatures, and Diseases of Biological Membranes, San Diego, CA, USA.
2010-2013 • F1000 Associate Faculty Member. Regularly contributing evaluation of papers published in biological sciences to the Faculty of 1000 Biology.